Senior Scientist
Talentmark
Company:
Our client is one of the world's premier innovative biopharmaceutical companies, discovering, developing and providing over 160 different medicines, vaccines and consumer healthcare products to help improve the lives of millions of people in the UK and around the world every year.
Salary:
Up to £20.66 per hour (PAYE) or £23.15 per hour (Umbrella)
Senior Scientist (Biopharmaceutics Modelling & Simulation) Role:
- Develop and apply PBBM/PBPK models using Simcyp, GastroPlus, or similar software.
- Predict oral absorption, food effect, bioavailability, and virtual bioequivalence.
- Run model calibration, sensitivity analysis, and uncertainty assessments.
- Work with lab scientists to design and interpret in vitro studies.
- Support development of clinically relevant dissolution methods.
- Present modelling outcomes in reports, presentations, and regulatory documents.
- PhD or MSc in Pharmaceutical Sciences, Biopharmaceutics, Pharmacokinetics, or related field.
- Expertise in PBPK, PBBM, pharmacometrics, or model-informed drug development.
- Strong grasp of oral absorption, dissolution, permeability, and pharmacokinetics.
- Hands-on experience with Simcyp, GastroPlus, PK-Sim, or similar platforms.
- Strong scientific communication skills, with evidence of publications/presentations and regulatory submission experience.
- Desirable: knowledge of Python/R/MATLAB, machine learning/data science experience, and exposure to multiple drug modalities (poorly soluble compounds, peptides, complex dosage forms).
For more information, or to apply for this Senior Scientist position please contact the Key Accounts Team on (phone number removed) or email (url removed). Please quote reference 202 893.
It is essential that applicants hold entitlement to work in the UK.
Please note: This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check.
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